Updated: Apr 2
In the next article, I going to talk about 3 amazing natural compounds you can use to reverse your biological age, build muscle and increase stamina. I wrote it thinking in people practicing bodybuilding and intermittent fasting or long fasts, which are pretty beneficial for reducing insulin levels, activate the longevity genes, autophagy, and boost growth hormone.
But I wrote the next document just thinking of people interested to build the muscles for any reason, for example, apigenin is excellent to build again atrophied muscles or reverse flabby skin and by taking the next compounds through diet or supplementation you can reverse your body age as well and increase your muscles if you work out often.
They are safe, Apigenin is found in Celery, Creatine in fish, and Ursolic acid in apples. On this blog, we only promote vegan-friendly supplements as the creatine supplement shown below which is very beneficial for maintaining mitochondria healthy. Because one of the leading theories about aging is that it is caused by the decline of mitochondrial function, so I consider it a powerful anti-aging compound. So, let´s talk about them...
Apigenin has been used as a traditional medicine for centuries. Recently, apigenin is widely investigated for its anti-cancer activities and low toxicity because It is reported to suppress various human cancers in vitro and in vivo by multiple biological effects, such as triggering cell apoptosis and autophagy, inducing cell cycle arrest, suppressing cell migration and invasion, and stimulating an immune response what is pretty beneficial to control cancer, but...
What is Apigenin ?
Apigenin is a flavonoid abundant in many fruits, vegetables, and herbs like parsley and celery. Quite pretty beneficial for the organism, it is anti-inflammatory, antioxidant, antibacterial, antiviral, and helps to reduce blood pressure. It has anti-aging effects as well like decreasing the enzyme CD38 or enhancing autophagy and it improves muscle building especially for people with muscular atrophy and sagging skin.
A high number of studies carried out over the years have indicated that apigenin has many interesting pharmacological activities and nutraceutical potential. As an example, its properties as an antioxidant are well known, and it can also be a therapeutic agent to overcome diseases like inflammation, autoimmune, neurodegenerative disease, and even several types of cancers like breast cancer.
Among the wide variety of phenolic compounds, apigenin is one of the most renowned, with countless nutritional and organoleptic characteristics. Nonetheless and more interestingly, it can also contribute with its beneficial health properties, which could lead to a possible inclusion in nutraceutical formulations. Nutraceuticals is a broad umbrella term that is used to describe any product derived from food sources with extra health benefits in addition to the basic nutritional value found in foods.
How does Apigenin help to build muscle ?
Several studies have shown that various phytochemicals like apigenin stimulate skeletal muscle hypertrophy and myogenic differentiation. These findings suggest that supplementation with phytochemicals in addition to specific proteins or amino acids may represent a potential therapeutic strategy for the prevention of muscle loss. Apigenin and Ursolic acid are 2 phytochemicals that accelerate muscular gain through exercise.
Muscle mass and strength are reduced with aging, movement decrease, and obesity. And because skeletal muscle strength is inversely associated with all-cause mortality in men, the prevention of muscle loss may contribute to the improvement of life quality, and attenuate chronic disease and mortality for the aged. Apigenin helps to increase the size of your skeletal muscle through a growth in the size of its component cells according to this study.
How does Apigenin help to reverse aging ?
Apigenin induces autophagy, which is when your body cleans out old and damaged parts of the cell to renew them. What improves your skin, organs and energy levels. It is a strategic method for reversing your biological age because of the removal of senescent cells. If you never heard about senescent cells, please read this article with a lot of valuable information.
Autophagy also cleans out old infected cells, mold, fungus, viruses, bacteria out the cell, so it's one of the greatest anti-aging processes and it is stimulated by intermittent fasting but it is also stimulated by certain phytonutrients like apigenin. Which inhibits as well the enzyme CD38 what has a very positive impact on the increase of NAD+ What makes Apigenin a good complement if you are taking NR or NMN supplementation.
Apigenin can attenuate inflammation, which is associated with many chronic diseases of aging. Flavonoids like apigenin were recently shown to reduce senescence-associated secretory phenotype (SASP) that can drive or exacerbate several age-related pathologies, including cancer. Apigenin as well could represent a novel tool to delay the onset of Alzheimer’s disease or slow down its progression.
How to take Apigenin ?
As an anti-aging coach, I recommend taking apigenin through the diet, especially in the last meal of the day, and it is included in oranges, onions, basil, thyme, parsley, celery, and chamomile tea. The only supplement I found with apigenin is this one which dose is 50mg that I recommend taking with an empty stomach, one hour after the last meal of the day.
A high number of studies carried out over the years have indicated that apigenin has many interesting pharmacological activities and nutraceutical potential. As an example, its properties as an antioxidant are well known, and it can also be a therapeutic agent to overcome diseases like inflammation, autoimmune, neurodegenerative disease, and even several types of cancers. According to this report on the therapeutic potential of Apigenin.
This is the compound that I mainly recommend to vegan bodybuilders because improves strength, increases lean muscle mass, helps the muscles recover more quickly during exercise, and improves mitochondria function. It is the only substance on this article that I recommend taking in supplementation because is mostly in animal-derived foods but I found vegan-friendly supplements like this one when I was writing this article with tips to maintain active mitochondria function for reversing the biological age. So, let's get deep into it.
What is creatine ?
Creatine is an amino acid located mostly in your body's muscles as well as in the brain. We naturally produce daily about 1 to 2 grams in our kidneys, liver, and pancreas. And can be absorbed by consuming red meats, salmon, or supplements. Then 90-95% of the creatine absorbed by your body goes to your muscles. Taking creatine as a supplement is very popular among athletes and bodybuilders in order to gain muscle, enhance strength and boost your workout performance.
Creatine promotes the production of ATP and by increasing the amount of ATP in your cells you become stronger, and energetic which facilitates your working out routine. Compared to just training alone creatine can double your lean muscle gains and strength. In addition, it can help to reduce body fat by 3.2% and increase your mental performance by increasing the ATP, which makes your brain has better clarity of thinking and better focus.
Creatine directly stimulates muscle building which makes this compound be the most optimal to take for bodybuilders and as well for reversing the biological age because the reduction of mitochondria function has a direct connection with aging. So, it is important to maintain NAD+ levels high and a good mitochondria function. And if you never hear about NAD+ and that the life expectancy for people that born today is around 200 years, check out this article.
How does creatine help to build muscle ?
There are over 300 studies that prove that if you consume creatine monohydrate in a dose of roughly 5 grams a day for 2 or 3 months you will get a significant increase in lean body mass increase in strength and even in muscular endurance without gain any fat from it. It is purely anabolic fuel that only increases lean body mass without having any effect on the fat mass.
Research shows that supplementing with creatine can double your strength and lean muscle gains when compared to training alone. It is a great supplement to have the energy to work out to increase muscle mass because gives you the energy you need, the muscular strength that facilitates the training, and then helps internal to the muscle to gain structure. Taking creatine in combination with a system like this one designed for doubling your muscle growth will help to lean muscle faster than ever before.
It is also recommended for the elderly to increase the lean body and strength that normally is reduced with the age. It is a very safe supplement that even children can take, but vegetarians and vegans especially need it because as well that vitamin B12, most of the sources of Creatine are animals. And the benefits of building muscle are so amazing that taking creatine supplementation definitely going to increase the size of your muscles faster.
How does creatine help to reverse aging ?
Creatine supplementation protects against cognitive decline, congestive heart failure, and helps you to reduce insulin levels and protects you against muscle loss. Creatine has the power of delaying neurodegenerative disease, strengthening memory function and intellectual capabilities. The main support of Creatine on the body is by increasing energy levels what improves mental and physical performance.
It enhances mitochondrial function by increasing ATP especially when you do exercise which is also important for the health of your mitochondria. The part of your cells that generates the energy you feel. There is where glucose or ketones are converted into energy and this energy determines your whole performance that normally is reduced when you get older.
Supplementing with creatine restores the energy loss that is at the root of many age-related diseases helping to maintain adequate levels of high-energy phosphate-containing molecules in tissues with especially high energy consumption, such as the heart, brain, and muscle. High levels of creatine support the body’s production of Adenosine triphosphate (ATP) which is the source of energy for use and storage at the cellular level.
How to take creatine ?
If it is your first time taking creatine in supplementation and you want to increase your muscle size fast start by consuming 20 grams per day during a week and then reduce the amount to 5 grams every day but if you do not want to increase your muscles and you are only interested to support your mitochondria function and enjoy the benefits of having more energy just consume a daily dose of 3 to 5 grams per day at any time is okay.
Ursolic acid could be a great natural supplement to take if you want to burn fat, lean muscle, and support your cardiovascular health. Cardiovascular Diseases are the major contributors to mortality and morbidity in the world, decreasing quality of life and increasing social and economic costs. In this study is shown how beneficial is ursolic acid for the brain, to prevent cancer, and reverse diabetes and obesity, which are aged-related conditions.
What is ursolic acid ?
Ursolic acid (UA) is a natural triterpene compound found in various fruits and vegetables with great beneficial effects, which include anti-inflammatory, anti-oxidant, anti-apoptotic, and anti-carcinogenic effects. It can be used as an alternative medicine for the treatment and prevention of cancer, obesity/diabetes, cardiovascular disease, brain disease, liver disease, and muscle wasting (sarcopenia).
Ursolic acid is found naturally in large quantities on apple peels but as well in other fruits and plants like cranberries, prunes, basil, bilberries, peppermint, rosemary, lavender, and thyme. Ursolic Acid (UA) ameliorates skeletal muscle performance through satellite cells proliferation and cellular energy status. A 10% increase in muscle mass and 30% increase in muscle strength was seen in a study where mice were fed a diet consisting of 0.27% ursolic acid.
How does ursolic acid help to build muscle ?
Taking ursolic acid supplementation will not only help build established muscle, but it can also make a muscle larger. Ursolic acid turn on genes that promote muscle building and burn and reduce fat. These genes are especially beneficial to build tissue on people with muscular atrophy especially those who took chemotherapy or suffer anorexia, so this is how this compound available in apple peels supports the muscles.
Ursolic acid increased Akt activity in skeletal muscle and C2C12 skeletal myotubes in mice fed high fat and it has also shown to increase skeletal muscle formation and energy consumption in obesity caused by diet in mice according to this study. From these results, it is claimed that the compound might be useful for metabolic disorders such as skeletal muscle atrophy, obesity, type2 diabetes, and nonalcoholic fatty liver disease.
This can be a great supplement if you are interested to burn fat or build your muscles because of aging, diabetes or cancer. But it should be mixed with exercise to have a real effect on the muscles and if you do not have time to spend in the gym try a program like
How does ursolic acid help to reverse aging ?
Ursolic acid is pretty beneficial for improving the condition of your cardiovascular system and brain. It also helps in cancer prevention. Recent trends in studies on UA have indicated the beneficial effects of the compound on autophagy and apoptosis in human breast cancer cell lines. It has shown great benefits in the inhibition of cell growth and induction of apoptosis in several cancer models. According to this study Ursolic acid was recently demonstrated to potentiate TRAIL-induced apoptosis in cancer cells.
In recent years, several in vivo and in vitro studies have demonstrated that ursolic acid has anti-inflammatory, antioxidant, and chemotherapeutic properties in various types of cancer, and neuroprotective activities. Furthermore, has been shown in vivo studies to suppress tumor invasion, to be chemopreventive, and to inhibit experimental metastasis of esophageal carcinoma. So, it can be a good supplement to take for people in the 40s interested to support their muscles and protect at the same time the heart, brain and prevent cancer.
How to take ursolic acid ?
The best time to take ursolic acid in supplement is during the morning between 150 to 200 mg. It is recommended to take 2 hours before the fitness training to have a better effect on your muscles. The dose of this supplement is 50mg and they suggest a dose of 200 mg in the morning and 200 mg at night, but I recommend you only take it once in the morning or afternoon if you work out during the night but the best is to incorporate in your diet the foods that contain it. But if you want to consume it to prevent some diseases take 400 mg a day.
The best option to build your muscles is taking Creatine which will give you energy and strength that will facilitate the training. If you are vegetarian or vegan take the supplement because it is contained in animals and even if your body produces it, Creatine is quite beneficial for your mitochondria, the powerhouse of your body. And ursolic acid could be a great supplement to take as well and apigenin I will consume through diet.
If want to know more herbs that can help you to build your muscles check this article with more vegan-friendly supplements you can take to build muscle mass. Also, visit our store here with devices that improve 1000% more the benefits of the water by saturating the beverage with life energy what improves the taste as well. These devices protect your body from energies produced by Electromagnetic pollution that deteriorates you.
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